The Clarke Group

Publications

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  • Currently displaying 1 - 20 of 167 publications
Author(s)
Publication title
Journal Name
Publication year
Selective Affimers Recognise the BCL‐2 Family Proteins BCL‐xL and MCL‐1 through Noncanonical Structural Motifs**
JA Miles, F Hobor, CH Trinh, J Taylor, C Tiede, PR Rowell, BR Jackson, FA Nadat, P Ramsahye, HF Kyle, BIM Wicky, J Clarke, DC Tomlinson, AJ Wilson, TA Edwards
Chembiochem : a European journal of chemical biology
(2020)
22
(doi: 10.1002/cbic.202000585)
Disorder in a two-domain neuronal Ca 2+ -binding protein regulates domain stability and dynamics using ligand mimicry
L Staby, KR Kemplen, A Stein, M Ploug, J Clarke, K Skriver, PO Heidarsson, BB Kragelund
Cellular and molecular life sciences : CMLS
(2020)
78
(doi: 10.1007/s00018-020-03639-z)
The folding and unfolding behavior of ribonuclease H on the ribosome
MK Jensen, AJ Samelson, A Steward, J Clarke, S Marqusee
The Journal of biological chemistry
(2020)
295
(doi: 10.1074/jbc.ra120.013909)
Spontaneous oligomerization of BAK/BAX is suppressed by hetero-dimerization with MCL-1
BIM Wicky, K Gupta, TOC Kwan, CV Robinson, J Clarke
(2019)
(doi: 10.1101/756874)
Extrinsic Conditions Influence the Self-Association and Structure of IF1, the Regulatory Protein of Mitochondrial ATP Synthase
V Boreikaite, BIM Wicky, IN Watt, J Clarke, JE Walker
Proceedings of the National Academy of Sciences
(2019)
116
(doi: 10.1073/pnas.1903535116)
Adaptation of Proteins to the Cold in Antarctic Fish: A Role for Methionine?
C Berthelot, J Clarke, T Desvignes, H William Detrich, P Flicek, LS Peck, M Peters, JH Postlethwait, MS Clark
Genome biology and evolution
(2019)
11
(doi: 10.1093/gbe/evy262)
Folding pathway of an Ig domain is conserved on and off the ribosome.
P Tian, A Steward, R Kudva, T Su, PJ Shilling, AA Nickson, JJ Hollins, R Beckmann, G von Heijne, J Clarke, RB Best
Proceedings of the National Academy of Sciences
(2018)
115
(doi: 10.1073/pnas.1810523115)
Non-Native Cooperative Interactions Modulate Protein Folding Rates
F Bruno da Silva, VG Contessoto, VM de Oliveira, J Clarke, VBP Leite
The Journal of Physical Chemistry B
(2018)
122
(doi: 10.1021/acs.jpcb.8b08990)
Investigating the Effect of Chain Connectivity on the Folding of a Beta-Sheet Protein On and Off the Ribosome.
AP Marsden, JJ Hollins, C O'Neill, P Ryzhov, S Higson, CATF Mendonça, TO Kwan, LG Kwa, A Steward, J Clarke
Journal of Molecular Biology
(2018)
430
(doi: 10.1016/j.jmb.2018.10.011)
Promiscuous and Selective: How Intrinsically Disordered BH3 Proteins Interact with Their Pro-survival Partner MCL-1
L Dahal, TOC Kwan, JJ Hollins, J Clarke
Journal of molecular biology
(2018)
430
(doi: 10.1016/j.jmb.2018.04.004)
Folding and binding pathways of BH3-only proteins are encoded within their intrinsically disordered sequence, not templated by partner proteins
MD Crabtree, CATF Mendonça, QR Bubb, J Clarke
J Biol Chem
(2018)
293
(doi: 10.1074/jbc.RA118.002791)
Author Correction: Protein-peptide association kinetics beyond the seconds timescale from atomistic simulations
F Paul, C Wehmeyer, ET Abualrous, H Wu, MD Crabtree, J Schöneberg, J Clarke, C Freund, TR Weikl, F Noé
Nat Commun
(2018)
9
(doi: 10.1038/s41467-018-03452-0)
Conservation of Folding Mechanism in Cotranslational Folding of Titin I27
P Tian, A Steward, J Clarke, RB Best
Biophysical Journal
(2018)
114
(doi: 10.1016/j.bpj.2017.11.3242)
Phosphorylation of the IDP KID modulates affinity for KIX by increasing the lifetime of the complex
L Dahal, SL Shammas, J Clarke
Biophys J
(2017)
113
(doi: 10.1016/j.bpj.2017.10.015)
Promiscuous but selective: how intrinsically disordered BH3-only proteins regulate apoptosis through binding to BCL-2 like proteins
L Dahal, J Clarke
PROTEIN SCIENCE
(2017)
26
pKID Binds to KIX via an Unstructured Transition State with Nonnative Interactions.
L Dahal, TOC Kwan, SL Shammas, J Clarke
Biophysical Journal
(2017)
113
(doi: 10.1016/j.bpj.2017.10.016)
Disorder, Evolution and Plasticity: Biophysical Signatures of the Arbitration of Apoptosis
B Wicky, T Kwan, J Clarke
PROTEIN SCIENCE
(2017)
26
Protein-peptide association kinetics beyond the seconds timescale from atomistic simulations.
F Paul, C Wehmeyer, ET Abualrous, H Wu, MD Crabtree, J Schöneberg, J Clarke, C Freund, TR Weikl, F Noé
Nature communications
(2017)
8
(doi: 10.1038/s41467-017-01163-6)
Affinity of IDPs to their targets is modulated by ion-specific changes in kinetics and residual structure.
BIM Wicky, SL Shammas, J Clarke
Proc Natl Acad Sci U S A
(2017)
114
(doi: 10.1073/pnas.1705105114)
Mechanistic studies of folding upon binding
J Clarke
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Yusuf Hamied Department of Chemistry
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CB2 1EW
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