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- Currently displaying 81 - 100 of 166 publications
Experiments suggest that simulations may overestimate electrostatic contributions to the mechanical stability of a fibronectin type III domain.
Journal of Molecular Biology
(2007)
371
851
(doi: 10.1016/j.jmb.2007.06.015)
Designing an extracellular matrix protein with enhanced mechanical stability
Proceedings of the National Academy of Sciences
(2007)
104
9633
(doi: 10.1073/pnas.0609901104)
The folding and evolution of multidomain proteins.
Nat Rev Mol Cell Biol
(2007)
8
319
(doi: 10.1038/nrm2144)
Mechanical unfolding of proteins: insights into biology, structure and folding
Curr Opin Struct Biol
(2007)
17
58
(doi: 10.1016/j.sbi.2007.01.006)
Single molecule studies of protein folding using atomic force microscopy.
Methods in Molecular Biology Clifton N J
(2007)
350
139
(doi: 10.1385/1-59745-189-4:139)
Apparent cooperativity in the folding of multidomain proteins depends on the relative rates of folding of the constituent domains.
Proceedings of the National Academy of Sciences
(2006)
103
18113
(doi: 10.1073/pnas.0604580103)
BPPred: a Web-based computational tool for predicting biophysical parameters of proteins.
Protein Science
(2006)
16
125
(doi: 10.1110/ps.062383807)
Spectrin domains lose cooperativity in forced unfolding.
Biophysical journal
(2006)
92
571
(doi: 10.1529/biophysj.106.093690)
Using model proteins to quantify the effects of pathogenic mutations in Ig-like proteins
Journal of Biological Chemistry
(2006)
281
24216
(doi: 10.1074/jbc.m603593200)
Structural comparison of the two alternative transition states for folding of TI I27.
Biophysical Journal
(2006)
91
263
(doi: 10.1529/biophysj.105.077057)
The folding pathway of spectrin R17 from experiment and simulation: using experimentally validated MD simulations to characterize States hinted at by experiment.
Journal of molecular biology
(2006)
359
159
(doi: 10.1016/j.jmb.2006.03.011)
Complex Folding Kinetics of a Multidomain Protein
Biophys J
(2005)
90
2120
(doi: 10.1529/biophysj.105.072710)
The importance of sequence diversity in the aggregation and evolution of proteins.
Nature
(2005)
438
878
(doi: 10.1038/nature04195)
Mechanical unfolding of TNfn3: the unfolding pathway of a fnIII domain probed by protein engineering, AFM and MD simulation.
Journal of Molecular Biology
(2005)
350
776
(doi: 10.1016/j.jmb.2005.04.070)
Cooperative Folding in a Multi-domain Protein
J Mol Biol
(2005)
349
1045
(doi: 10.1016/j.jmb.2005.04.028)
The remarkable mechanical strength of polycystin-1 supports a direct role in mechanotransduction
Journal of Molecular Biology
(2005)
349
861
(doi: 10.1016/j.jmb.2005.04.008)
What contributions to protein side-chain dynamics are probed by NMR experiments? A molecular dynamics simulation analysis.
Journal of Molecular Biology
(2005)
349
185
(doi: 10.1016/j.jmb.2005.03.001)
Energy landscapes and solved protein-folding problems - Discussion
PHILOS T ROY SOC A
(2005)
363
464
Energy landscapes and solved proteinfolding problems
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
(2005)
363
453
(doi: 10.1098/rsta.2004.1502)
The remarkable mechanical strength of polycystin-1 suggests a novel mechanism for mechanotransduction
BIOPHYSICAL JOURNAL
(2005)
88
585A