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Currently displaying 81 - 100 of 167 publications

Distinguishing Specific and Nonspecific Interdomain Interactions in Multidomain Proteins

LG Randles, S Batey, A Steward, J Clarke

Biophys J

(2007)

622

(doi: 10.1529/biophysj.107.119123)

Experiments suggest that simulations may overestimate electrostatic contributions to the mechanical stability of a fibronectin type III domain

SP Ng, J Clarke

Journal of Molecular Biology

(2007)

371

851

(doi: 10.1016/j.jmb.2007.06.015)

Designing an extracellular matrix protein with enhanced mechanical stability.

SP Ng, KS Billings, T Ohashi, MD Allen, RB Best, LG Randles, HP Erickson, J Clarke

Proc Natl Acad Sci U S A

(2007)

104

9633

(doi: 10.1073/pnas.0609901104)

The folding and evolution of multidomain proteins

J-H Han, S Batey, AA Nickson, SA Teichmann, J Clarke

Nature Reviews Molecular Cell Biology

(2007)

319

(doi: 10.1038/nrm2144)

Mechanical unfolding of proteins: insights into biology, structure and folding

JR Forman, J Clarke

Current Opinion in Structural Biology

(2007)

(doi: 10.1016/j.sbi.2007.01.006)

Single molecule studies of protein folding using atomic force microscopy.

SP Ng, LG Randles, J Clarke

Methods in molecular biology (Clifton, N.J.)

(2007)

350

139

(doi: 10.1385/1-59745-189-4:139)

Apparent cooperativity in the folding of multidomain proteins depends on the relative rates of folding of the constituent domains.

S Batey, J Clarke

Proc Natl Acad Sci U S A

(2006)

103

18113

(doi: 10.1073/pnas.0604580103)

BPPred: a Web-based computational tool for predicting biophysical parameters of proteins.

CD Geierhaas, AA Nickson, K Lindorff-Larsen, J Clarke, M Vendruscolo

Protein Science

(2006)

125

(doi: 10.1110/ps.062383807)

Spectrin Domains Lose Cooperativity in Forced Unfolding

LG Randles, RWS Rounsevell, J Clarke

Biophysical journal

(2006)

571

(doi: 10.1529/biophysj.106.093690)

Using model proteins to quantify the effects of pathogenic mutations in Ig-like proteins.

LG Randles, I Lappalainen, SB Fowler, B Moore, SJ Hamill, J Clarke

J Biol Chem

(2006)

281

24216

(doi: 10.1074/jbc.m603593200)

Structural Comparison of the Two Alternative Transition States for Folding of TI I27

CD Geierhaas, RB Best, E Paci, M Vendruscolo, J Clarke

Biophysical journal

(2006)

263

(doi: 10.1529/biophysj.105.077057)

The folding pathway of spectrin R17 from experiment and simulation: using experimentally validated MD simulations to characterize States hinted at by experiment.

KA Scott, LG Randles, SJ Moran, V Daggett, J Clarke

J Mol Biol

(2006)

359

159

(doi: 10.1016/j.jmb.2006.03.011)