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Currently displaying 81 - 100 of 166 publications

Distinguishing specific and nonspecific interdomain interactions in multidomain proteins

LG Randles, S Batey, A Steward, J Clarke

Biophysical journal

(2007)

622

(doi: 10.1529/biophysj.107.119123)

Experiments suggest that simulations may overestimate electrostatic contributions to the mechanical stability of a fibronectin type III domain.

SP Ng, J Clarke

Journal of Molecular Biology

(2007)

371

851

(doi: 10.1016/j.jmb.2007.06.015)

Designing an extracellular matrix protein with enhanced mechanical stability.

SP Ng, KS Billings, T Ohashi, MD Allen, RB Best, LG Randles, HP Erickson, J Clarke

Proceedings of the National Academy of Sciences

(2007)

104

9633

(doi: 10.1073/pnas.0609901104)

The folding and evolution of multidomain proteins.

J-H Han, S Batey, AA Nickson, SA Teichmann, J Clarke

Nature reviews. Molecular cell biology

(2007)

319

(doi: 10.1038/nrm2144)

Mechanical unfolding of proteins: insights into biology, structure and folding.

JR Forman, J Clarke

Current opinion in structural biology

(2007)

(doi: 10.1016/j.sbi.2007.01.006)

Single Molecule Studies of Protein Folding Using Atomic Force Microscopy

SP Ng, LG Randles, J Clarke

Methods Mol Biol

(2007)

350

139

(doi: 10.1385/1-59745-189-4:139)

Apparent cooperativity in the folding of multidomain proteins depends on the relative rates of folding of the constituent domains

S Batey, J Clarke

Proc Natl Acad Sci U S A

(2006)

103

18113

(doi: 10.1073/pnas.0604580103)

BPPred: A Web‐based computational tool for predicting biophysical parameters of proteins

CD Geierhaas, AA Nickson, K Lindorff-Larsen, J Clarke, M Vendruscolo

Protein Sci

(2006)

125

(doi: 10.1110/ps.062383807)

Spectrin Domains Lose Cooperativity in Forced Unfolding

LG Randles, RWS Rounsevell, J Clarke

Biophys J

(2006)

571

(doi: 10.1529/biophysj.106.093690)

Using Model Proteins to Quantify the Effects of Pathogenic Mutations in Ig-like Proteins* ♦

LG Randles, I Lappalainen, SB Fowler, B Moore, SJ Hamill, J Clarke

J Biol Chem

(2006)

281

24216

(doi: 10.1074/jbc.M603593200)

Structural Comparison of the Two Alternative Transition States for Folding of TI I27

CD Geierhaas, RB Best, E Paci, M Vendruscolo, J Clarke

Biophysical journal

(2006)

263

(doi: 10.1529/biophysj.105.077057)

The Folding Pathway of Spectrin R17 from Experiment and Simulation: Using Experimentally Validated MD Simulations to Characterize States Hinted at by Experiment

KA Scott, LG Randles, SJ Moran, V Daggett, J Clarke

Journal of Molecular Biology

(2006)

359

159

(doi: 10.1016/j.jmb.2006.03.011)