The Clarke Group

Publications

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  • Currently displaying 41 - 60 of 166 publications
Author(s)
Publication title
Journal Name
Publication year
Coupled folding and binding of the disordered protein PUMA does not require particular residual structure
JM Rogers, CT Wong, J Clarke
J Am Chem Soc
(2014)
136
(doi: 10.1021/ja4125065)
Mechanism of assembly of the non-covalent spectrin tetramerization domain from intrinsically disordered partners
SA Hill, LG Kwa, SL Shammas, JC Lee, J Clarke
Journal of Molecular Biology
(2014)
426
(doi: 10.1016/j.jmb.2013.08.027)
The Folding of a Family of Three-Helix Bundle Proteins: Spectrin R15 Has a Robust Folding Nucleus, Unlike Its Homologous Neighbours
LG Kwa, BG Wensley, CG Alexander, SJ Browning, BR Lichman, J Clarke
Journal of Molecular Biology
(2013)
426
(doi: 10.1016/j.jmb.2013.12.018)
Biophysics: Rough passage across a barrier
B Schuler, J Clarke
Nature
(2013)
502
(doi: 10.1038/nature12697)
Remarkably Fast Coupled Folding and Binding of the Intrinsically Disordered Transactivation Domain of cMyb to CBP KIX
SL Shammas, AJ Travis, J Clarke
J Phys Chem B
(2013)
117
(doi: 10.1021/jp404267e)
A Mechanistic Model for Amorphous Protein Aggregation of Immunoglobulin-like Domains
MB Borgia, AA Nickson, J Clarke, MJ Hounslow
J Am Chem Soc
(2013)
135
(doi: 10.1021/ja308852b)
Folding and Binding of an Intrinsically Disordered Protein: Fast, but Not 'Diffusion-Limited'
JM Rogers, A Steward, J Clarke
Journal of the American Chemical Society
(2013)
135
(doi: 10.1021/ja309527h)
Understanding pathogenic single-nucleotide polymorphisms in multidomain proteins--studies of isolated domains are not enough.
LG Randles, GJS Dawes, BG Wensley, A Steward, AA Nickson, J Clarke
FEBS Journal
(2013)
280
(doi: 10.1111/febs.12094)
Take home lessons from studies of related proteins
AA Nickson, BG Wensley, J Clarke
Curr Opin Struct Biol
(2012)
23
(doi: 10.1016/j.sbi.2012.11.009)
Slow, reversible, coupled folding and binding of the spectrin tetramerization domain.
SL Shammas, JM Rogers, SA Hill, J Clarke
Biophysical journal
(2012)
103
(doi: 10.1016/j.bpj.2012.10.012)
Localizing internal friction along the reaction coordinate of protein folding by combining ensemble and single-molecule fluorescence spectroscopy.
A Borgia, BG Wensley, A Soranno, D Nettels, MB Borgia, A Hoffmann, SH Pfeil, EA Lipman, J Clarke, B Schuler
Nature communications
(2012)
3
(doi: 10.1038/ncomms2204)
Protein folding: adding a nucleus to guide helix docking reduces landscape roughness.
BG Wensley, LG Kwa, SL Shammas, JM Rogers, J Clarke
Journal of Molecular Biology
(2012)
423
(doi: 10.1016/j.jmb.2012.08.003)
Learning from Nature to design new biomolecules
J Clarke, W Schief
Current Opinion in Structural Biology
(2012)
22
(doi: 10.1016/j.sbi.2012.07.001)
Separating the effects of internal friction and transition state energy to explain the slow, frustrated folding of spectrin domains
BG Wensley, LG Kwa, SL Shammas, JM Rogers, S Browning, Z Yang, J Clarke
Proceedings of the National Academy of Sciences of the United States of America
(2012)
109
(doi: 10.1073/pnas.1201793109)
Staphylococcal biofilm-forming protein has a contiguous rod-like structure.
DT Gruszka, JA Wojdyla, RJ Bingham, JP Turkenburg, IW Manfield, A Steward, AP Leech, JA Geoghegan, TJ Foster, J Clarke, JR Potts
Proceedings of the National Academy of Sciences
(2012)
109
(doi: 10.1073/pnas.1119456109)
Two immunoglobulin tandem proteins with a linking β-strand reveal unexpected differences in cooperativity and folding pathways
A Steward, Q Chen, RI Chapman, MB Borgia, JM Rogers, A Wojtala, M Wilmanns, J Clarke
Journal of Molecular Biology
(2012)
416
(doi: 10.1016/j.jmb.2011.12.012)
Single-molecule fluorescence reveals sequence-specific misfolding in multidomain proteins
MB Borgia, A Borgia, RB Best, A Steward, D Nettels, B Wunderlich, B Schuler, J Clarke
Nature
(2011)
474
(doi: 10.1038/nature10099)
Quantifying heterogeneity and conformational dynamics from single molecule FRET of diffusing molecules: recurrence analysis of single particles (RASP).
A Hoffmann, D Nettels, J Clark, A Borgia, SE Radford, J Clarke, B Schuler
Phys Chem Chem Phys
(2011)
13
(doi: 10.1039/c0cp01911a)
Studying the folding of multidomain proteins
S Batey, AA Nickson, J Clarke
All Life
(2010)
2
(doi: 10.2976/1.2991513)
Protein engineering and design: From first principles to new technologies
J Clarke, L Regan
Curr Opin Struct Biol
(2010)
20
(doi: 10.1016/j.sbi.2010.07.001)
Yusuf Hamied Department of Chemistry
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